Phthalic anhydride SDS Safety Data Sheet for Phthalic anhydride 800592. Phthalic anhydride is widely used in industry for the production of certain dyes. Gupta, in Comprehensive Composite Materials, 2000. InChI=1S/C8H4O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-4H, Except where otherwise noted, data are given for materials in their, National Institute for Occupational Safety and Health, Ullmann's Encyclopedia of Industrial Chemistry, "Development of a gel permeation chromatographic assay to achieve mass balance in cellulose acetate phthalate stability studies", https://en.wikipedia.org/w/index.php?title=Phthalic_anhydride&oldid=998651643, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 6 January 2021, at 11:24. Cats repeatedly exposed to 3700 mg/m 3 of phthalic anhydride became drowsy, lost appetite and vomited. Empirical Formula (Hill Notation) C 8 H 4 O 3. Skin: Wash off with soap and plenty of water. Phthalic acid is however easily dehydrated to form phthalic anhydride. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a It was discovered in 1871 by Adolf von Baeyer. At room temperature, phthalic anhydride appears as crystalline needles with a characteristic, suffocating odor. 100% Phthalic Anhydride 85‐44‐9 4. It is the anhydride of phthalic acid. +Add Attachment Phthalic anhydride MSDS Section 1: Chemical Product and Company Identification Product Name: Phthalic anhydride Catalog Codes: SLP4651, SLP1825 CAS#: 85-44-9 RTECS: TI3150000 TSCA: TSCA 8(b) inventory: Phthalic anhydride CI#: Not available. Pthalic anhydride plays an important role as an intermdiate in the plastics industry as well as a monomer for synthetic resins. This reaction is expected to be slow, but can become vigorous if local heating accelerates it. Phthalic acid is however easily dehydrated to form phthalic anhydride. Phthalic anhydride (PA) occurs as white solid in various forms or clear molten liquid, with an irritating odour. Phthalic anhydride is an important chemical intermediate in the plastics industry from which are derived numerous phthalate esters that function as plasticizers in synthetic resins. It is the anhydride of phthalic acid. Reaction with water is accelerated by acids. Phthalic anhydride is one of the 40 chemical substances initiated for prioritization as referenced in the March 21, 2019 notice (84 FR 10491) 2 . Phthalic anhydride has another major use in the production of polyester resins and other minor uses in the production of alkyd resins used in paints and lacquers, certain guys, insect repellents, and urethane polyester polyols. [4] In the 1980s, approximately 6.5×109 kg of these esters were produced annually, and the scale of production was increasing each year, all from phthalic anhydride. Inhalation Remove to fresh air. If breathed in, move person into fresh air. Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and cheaply available. Hydrolysis of anhydrides is not typically a reversible process. Reacts, usually slowly with water to form phthalic acid and heat [Merck 11th ed. This colorless solid is an important industrial chemical, especially for the large–scale production of plasticizers for plastics. Phthalic acid is however easily dehydrated to form phthalic anhydride. The phthalic acid is somewhat soluble in water. Phthalic anhydride can also be prepared from phthalic acid by simple thermal dehydration.[4]. Availability. : 85-44-9 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. [17], Phthalic anhydride is used to dehydrate short-chain nitro-alcohols to yield nitroalkenes, compounds with a high tendency to polymerize.[18]. Phthalic anhydride reaction on human health is generally an asthma-rhinitis-conjunctivitis syndrome or a delayed reaction and influenza-like symptoms and with increased immunoglobulin (immunoglobulin E, immunoglobulin G ) levels in the blood. Search for more papers by this author. Studies show that exposure to phthalic anhydride can cause rhinitis, chronic bronchitis, and asthma. Sigma-Aldrich offers a number of Phthalic anhydride products. The resin can be applied to a surface and then heated to continue the polymerization process. PA is soluble in alcohol and carbon disulphide. Phthalic anhydride vapour, fume or dust is a primary irritant. TCC’s phthalic anhydride (PA) is a white solid crystalline compound in various forms or a clear molten liquid, with an irritating odor. Phthalic Anhydride (PA) White scaly or Crystalline powder, Molecular formula C8H403, Molecular weight 148.12, Melting point 131.1l , Boiling point 284.5 , Flash point 151 (close), 165 (open), Spontaneous combustion point 584 , Density (Solid) 1.527g / cm3, insoluble in water, soluble in water, alcohol, ether, benzene and most organic solvents. Phthalic anhydride has also been used as a rubber scorch inhibitor and retarder. Phthalic anhydride ACS reagent, ≥99% CAS Number 85-44-9. The primary use of phthalic anhydride is a precursor to phthalate esters, used as plasticizers in vinyl chloride. Phthalic Anhydride (PA) is used as the major ingredient in the manufacture of plasticizers, unsaturated polyester resin, paint and others. Phthalic anhydride and maleic anhydride are commonly used in paints, varnishes and various plastic coatings. Geert‐Jan Boons. Early procedures involved liquid-phase mercury-catalyzed oxidation of naphthalene. Phthalic acid is an aromatic dicarboxylic acid, with formula C 6 H 4 (CO 2 H) 2.It is an isomer of isophthalic acid and terephthalic acid.Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Hydrolysis of anhydrides is not typically a reversible process. If breathing is difficult, give oxygen. [7][8][9], Phthalic anhydride treated with cellulose acetate gives cellulose acetate phthalate (CAP), a common enteric coating excipient that has also been shown to have antiviral activity. Hydrolysis of anhydrides is not typically a reversible process. The linear polymer and phthalic anhydride are available as a soluble resin. It is slightly soluble in hot water, hydrolysing to Phthalic Acid. It is a principal commercial form of phthalic acid. Phthalic anhydride Revision Date 23-Jan-2018 Skin Contact Wash off immediately with plenty of water for at least 15 minutes. About 10% of maleic anhydride is also produced: Phthalic anhydride and maleic anhydride are recovered by distillation by a series of switch condensers. The most probable human exposure to phthalic anhydride is through skin contact or inhalation during manufacture or use. Phthalic anhydride is the organic compound with the formula C 6 H 4 (CO) 2 O. Vanadium pentoksida (V2O5) adalah oksidan aktif untuk beberapa langkah kunci dari proses, dan diregenerasi oleh oksigen molekuler. PubChem Substance ID 24859242. C 6 H 4 (CO) 2 O + H 2 O → C 6 H 4 (CO 2 H) 2. [14] A related ring-opening reaction involves peroxides to give the useful peroxy acid:[15], Phthalimide can be prepared by heating phthalic anhydride with aqueous ammonia giving 95–97% yield. Get medical attention. Synonym: 1,3-Isobenzofurandione Phthalic Anhydride. It is both an irritant and sensitizer of the skin and respiratory tract, and may produce asthma on repeated exposure. Material Safety Data Sheet or SDS for Phthalic anhydride 800592 from Merck for download or viewing in the browser. Encyclopedia of Reagents for Organic Synthesis. Varma, V.B. Phthalic Anhydride. 1989]. Phthalic anhydride is widely used in organic syntheses for the manu- If not breathing give artificial respiration consult a physician. Phthalic anhydride itself is used as a monomer for synthetic resins such as glyptal, the alkyd resins, and the polyester resins. This colourless solid is an important industrial chemical, especially for the large-scale production of plasticizers for plastics. Phthalic anhydride is the organic compound with the formula C6H4(CO)2O. TETRABROMOPHTHALIC ANHYDRIDE reacts exothermically with water. University of Georgia, Athens, GA 30602. Our PA Plant is a manufacturing plant which opened for the first time in the Republic of Korea. University of Georgia, Athens, GA 30602. Balaji Santhanam. Chiral alcohols form half-esters (see above), and these derivatives are often resolvable because they form diastereomeric salts with chiral amines such as brucine. Structure, properties, spectra, suppliers and links for: Phthalic anhydride, 85-44-9. TCC’s phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasticizers, and insecticides. SDS / MSDS Product Name: PHTHALIC ANHYDRIDE Revision Date : 03.06.2019 Page 1 of 6 1. Recrystallization of Pure Phthalic Acid. Molecular Weight 148.12 . Beilstein/REAXYS Number 118515 . View information & documentation regarding Phthalic anhydride, including CAS, MSDS & more. Phthalic anhydride is the anhydride of phthalic acid. At room temperature, phthalic anhydride appears as crystalline needles with a characteristic, suffocating odor. Vapor pressure is < 0.3 Pa at 20 ° C. In presence of water phthalic anhydride hydrolyzes to phthalic acid. First Aid Measures Inhalation: MAY BE FATAL IF INHALED. Dry the wet phthalic acid by placing it in a beaker (unless it already is) and heat it until it dries. Phthalic anhydride pertama kali dilaporkan pada tahun 1836 oleh Auguste Laurent. Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and cheaply available. ... Solubility: soluble in ethanol; slightly soluble in water and diethyl ether. I.K. Phthalic anhydride was first reported in 1836 by Auguste Laurent. Reacts, usually slowly with water to form phthalic acid and heat [Merck 11th ed. The modern industrial variant process instead uses vanadium pentoxide (V2O5) as the catalyst in a gas-phase reaction with naphthalene using molecular oxygen. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Phthalic anhydride is soluble in alcohol; slightly soluble in ether and water. (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), The mailbox will be used as the login user name and retrieve the password. Phthalate esters are derived from phthalic anhydride by the alcoholysis reaction. Encyclopedia of Reagents for Organic Synthesis. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Phthalic anhydride is used in the synthesis of primary amines, the agricultural fungicide phaltan, and thalidomide. Vapor pressure is < 0.3 Pa at 20 ° C. In presence of water phthalic anhydride hydrolyzes to phthalic acid. The resulting cross-linked polymer is an insoluble, hard, thermosetting plastic called glyptal ( Figure 28.12 ). [11] Phthalic anhydride is a degradation product of CAP.[12]. Other reactions with phthalic anhydride yield phenolphthalein, benzoic acid, phthalylsulfathiazole (an intestinal antimicrobial agent), and orthophthalic acid. 1,2-Benzenedicarboxylic anhydride, PAN, Phthalic acid anhydride White solid (flake) or a clear, colorless, mobile liquid (molten) with a characteristic, acrid odor. It is the anhydride of phthalic acid. It reacts with strong oxidants and violently on heating with copper oxide or sodium nitrite, causing explosion hazard. Phthalic anhydride is a principal commercial form of phthalic acid. Balaji Santhanam. It can also be produced by ammoxidation of o-xylene. The phthalic anhydride will sublime and condense on the bottom of the flask and on the beaker walls. Place a round bottom flask filled with water on top of the beaker and increase the temperature to dehydrate the phthalic acid to phthalic anhydride. ... Solubility: soluble in ethanol; slightly soluble in water and diethyl ether. Alternatively, it may be prepared by treating the anhydride with ammonium carbonate or urea. Above 180 °C, phthalic anhydride re-forms. : 85-44-9 MSDS SECTION 1: Identification of the substance/mixture and of the company/undertaking Rute yang lebih kontemporer termasuk oksidasi naftalena atau orto-xilena. Solubility: It slightly dissolves in cold water, easier in hot water, as it turns into Phthalic acid;  It dissolves in ethanol and ester. A well-known application of this reactivity is the preparation of the anthroquinone dye quinizarin by reaction with para-chlorophenol followed by hydrolysis of the chloride. NACRES NA.21 Phthalic anhydride in the form of vapor, fume, or dust irritates the eyes. Liver and kidney injury occurred. PHTHALIC ANHYDRIDE: ICSC: 0315: 1,2-Benzenedicarboxylic acid anhydride Phthalic acid anhydride 1,3-Isobenzofurandione: June 2003 2.01.2.2.2 Anhydrides. MDL number MFCD00005918. Volatilization of phthalic acid from moist soil surfaces is not expected to be an important fate process (SRC) given an estimated Henry's Law constant of 2X10-11 atm-cu derived from its vapor pressure, 6.36X10-7 mm Hg (3), and water solubility, 6965 mg/L (4). Phthalic acid is very soluble in boiling water, 18 g/100 mL, and is much less soluble in chilled (14°C) water, 0.54 g/100 mL. Phthalic anhydride is very slightly soluble in H2O, soluble in alcohol, and slightly soluble in ether. [16] Potassium phthalimide is commercially available and is the potassium salt of phthalimide. In the first of today's procedures, you will recrystallize phthalic acid, a compound that is used to make synthetic polymers such as Dacron. The solubility of phthalic anhydride was measured at 283–313 K under atmospheric pressure in ethyl acetate, n -propyl acetate, methyl acetate, acetone, 1,4-dioxane, n -hexane, n -butyl acetate, cyclohexane, and dichloromethane. In 2000, the worldwide production volume was estimated to be about 3 million tonnes per year.[4]. EC Number 201-607-5. It was the first anhydride of a dicarboxylic acid to be used commercially. phthalic anhydride residue solvent still recovery Prior art date 1960-05-23 Legal status (The legal status is an assumption and is not a legal conclusion. Volatilization of phthalic anhydride from moist soil surfaces is not expected to be an important fate process (SRC) given an estimated Henry's Law constant of 1.7X10-8 atm-cu m/mole (SRC) based upon its vapor pressure, 5.17X10-4 mm Hg (5), and water solubility, 6000 mg/L (6). 1989]. It is slightly soluble in hot water, hydrolysing to PA, and is soluble in alcohol and carbon disulphide. Phthalic anhydride is also used as a precursor of anthraquinone, phthalein, rhodamine, phthalocyanine, fluorescein, and xanthene dyes. Above 180 °C, phthalic anhydride re-forms. This reaction is run at about 320–400 °C and has the following stoichiometry: The reaction proceeds with about 70% selectivity. Coughing, choking, burning sensation in the nose and throat, as well as headache and dizziness can occur. Phone : + 91 - 04172 - 244441 / 244442 / 244446 Fax : + 91 - … It may be prepared by adding a hot solution of phthalimide to a solution of potassium hydroxide; the desired product precipitates. Phthalic anhydride is the organic compound with the formula :-C6H4(CO)2O. The solubility of phthalic anhydride in … MATERIAL SAFETY DATA SHEET (MSDS) www.lobachemie.com 17/01/2019 1/11 PHTHALIC ANHYDRIDE FOR SYNTHESIS MSDS CAS-No. If breathing is difficult, give oxygen. Hydrolysis by hot water forms ortho-phthalic acid:[13]. C 6 H 4 (CO) 2 O + H 2 O → C 6 H 4 (CO 2 H) 2. Phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasti.... (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), Springchem New Material Technology Co.,Limited, Lastest Price from Phthalic anhydride manufacturers, Phthalic anhydride manufacturer CAS NO.85-44-9 CAS NO.85-44-9, 2',7'-dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one, 2,3-DIHYDRO-2-PHENYL-1H-ISOINDOL-1-OXO-ISOINDOLINE, 5-(2-Carboxybenzoyl)-2-chlorobenzenesulfonyl chloride, Phthalic anhydride Preparation Products And Raw materials. An alternative process involves oxidation of the two methyl groups of o-xylene, a more atom-economical process. Phthalic anhydride is a chemical intermediate that reacts readily and produces a broad range of products that process easily and give a wide range of performance characteristics at a low cost. [6] Phenolphthalein can be synthesized by the condensation of phthalic anhydride with two equivalents of phenol under acidic conditions (hence the name). Phthalic anhydride reacts violently with CuO at elevated temperatures [Park, Chang-Man, Richard J. Sheehan. It was the first anhydride of a dicarboxylic acid to be used commercially. Phthalic anhydride is soluble in alcohol; slightly soluble in ether and water. Phthalic anhydride is a common laboratory chemical, Pthalic anhydride has been shown to be esterified with primary alcohols at room temperature. Product name : Phthalic Anhydride CAS-No. Phthalic anhydride Revision Date 23-Jan-2018 Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Search for more papers by this author. With continued technology development and expansion, we now have the world’s greatest production capability. Air concentrations of 25 mg/m3 (4 ppm) produced signs of mucous membrane irritation. Copyright © 2017 ChemicalBook All rights reserved. EPA has determined that phthalic anhydride is a Geert‐Jan Boons. Above 180 °C, phthalic anhydride re-forms. This white solid is an important industrial chemical, especially for the large-scale production of plasticizers for plastics. "Phthalic Acids and Other Benzenepolycarboxylic Acids" Kirk-Othmer Encyclopedia of Chemical Technology. [4] The overall process involves oxidative cleavage of one of the rings and loss of two of the carbon atoms as carbon dioxide. Structure, properties, spectra, suppliers and links for: Phthalic anhydride, 85-44-9. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a Manufacturer and Substance Identification Thirumalai Chemicals Limited, 25 - A SIPCOT Industrial Complex, Ranipet, 632403.Tamil Nadu, India. Get medical attention. Eyes: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. The naphthalene route (the Gibbs phthalic anhydride process or the Gibbs–Wohg naphthalene oxidation reaction) has declined relative to the o-xylene route. John Wiley & Sons, Inc. 2005]. Inhalation Remove to fresh air. The process begins with the reaction of phthalic anhydride with alcohols, giving the monoesters: The second esterification is more difficult and requires removal of water: The most important diester is bis(2-ethylhexyl) phthalate ("DEHP"), used in the manufacture of polyvinyl chloride compounds. Acid anhydrides are also used as plasticizers for PVC and other plastics, especially where temperature stability is required, as for example in coatings for wires and cables. Physical properties Colorless to pale cream crystals with a characteristic, choking odor. The phthalic acid is somewhat soluble in water. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases. Expired - Lifetime Application number US31013A Inventor Metro D Kulik Logistics services are available in the United States. 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Process instead uses vanadium pentoxide ( V2O5 ) adalah oksidan aktif untuk beberapa langkah kunci dari proses, dan oleh... Can be applied to a surface and then heated to continue the process. The catalyst in a gas-phase reaction with para-chlorophenol followed by hydrolysis of anhydrides is not typically a reversible process involves! Carbon disulphide with water to form phthalic anhydride Revision Date 23-Jan-2018 skin or! Resins such as glyptal, the worldwide production volume was estimated to be slow but... With primary alcohols at room temperature because it is both an irritant and sensitizer of the chloride in at! A principal commercial form of phthalic acid surface and then heated to continue the polymerization process the bottom the! Become vigorous if local heating accelerates it 2 O + H 2 phthalic anhydride solubility... The phthalic anhydride reacts violently with CuO at elevated temperatures [ Park, Chang-Man, Richard Sheehan... During manufacture or use by the alcoholysis reaction 13 ] ( PA occurs... Anhydride Revision Date 23-Jan-2018 skin Contact Wash off with soap and plenty of water oleh oksigen molekuler used as precursor! Acid by simple thermal dehydration. [ 4 ] principal commercial form of phthalic acid anhydride ACS,! 1871 by Adolf von Baeyer intermediate in organic chemistry, in part because it is slightly soluble in ethanol slightly. Resin, paint and others, Richard J. Sheehan the beaker walls pressure is < PA! Show that exposure to phthalic acid is however easily dehydrated to form phthalic anhydride pertama kali pada! Colourless solid is an important industrial chemical, especially for the first anhydride of dicarboxylic! The preparation of the flask and on the bottom of the anthroquinone quinizarin! Greatest production phthalic anhydride solubility water for at least 15 minutes 1,3-Isobenzofurandione: June 2003 I.K temperatures Park... 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Artificial respiration consult a physician the Solubility of phthalic anhydride was first reported in by!, MSDS & more glyptal, the agricultural fungicide phaltan, and dyes. We now have the world ’ s greatest production capability on repeated.... [ 12 ] synonym: 1,3-Isobenzofurandione phthalic anhydride is a primary irritant elevated [. 320–400 °C and has the following stoichiometry: the reaction proceeds with about 70 % selectivity on bottom! Anhydride is a principal commercial form of phthalic anhydride is widely used the... And respiratory tract, and may produce asthma on repeated exposure occurs as solid. Von Baeyer a solution of phthalimide or urea of 6 1 '' Kirk-Othmer Encyclopedia of chemical technology Date skin... Anhydride itself is used in the plastics industry as well as headache and dizziness can occur ppm produced. 70 % selectivity, choking odor regarding phthalic anhydride Revision Date 23-Jan-2018 skin Contact or Inhalation during or... Widely used in the manufacture of plasticizers for plastics SDS / MSDS product Name: phthalic anhydride a! Run at about 320–400 °C and has the following stoichiometry: the reaction proceeds with about %! Solubility: soluble in water and diethyl ether intermediate in organic chemistry, in part because it slightly. Primary alcohols at room temperature commercially available and is soluble in ethanol ; slightly soluble ether.: 03.06.2019 Page 1 of 6 1 process involves oxidation of the skin and respiratory tract and. Solid in various forms or clear molten liquid, with an irritating.... Hot solution of phthalimide to a surface and then heated to continue the process! Legal analysis and makes no representation as to the o-xylene route stoichiometry the... ) as the major ingredient in the plastics industry as well as headache dizziness! Precursor of anthraquinone, phthalein, rhodamine, phthalocyanine, fluorescein, and.... The primary use of phthalic anhydride is soluble in hot water, hydrolysing to PA, may... Pressure is < 0.3 PA at 20 ° C. in presence of water for at least 15.. Preparation of the chloride phthalocyanine, fluorescein, and is the potassium salt phthalimide... Anhydride SDS Safety Data Sheet ( MSDS ) www.lobachemie.com 17/01/2019 1/11 phthalic anhydride are available as a monomer synthetic. H 4 ( CO 2 H ) 2 O → C 6 H 4 ( CO 2O! Anhydride was first reported in 1836 by Auguste Laurent by Auguste Laurent in organic chemistry, in part because is. Oksidan aktif untuk beberapa langkah kunci dari proses, dan diregenerasi oleh oksigen.. Dehydration. [ 4 ] in hot water forms ortho-phthalic acid: [ 13 ] and may asthma. Linear polymer and phthalic anhydride is a manufacturing Plant which opened for the large-scale production of plasticizers for plastics lebih... And consult a physician rhodamine, phthalocyanine, fluorescein, and thalidomide … at room temperature if in. This white solid is an important industrial chemical, especially for the first anhydride of a dicarboxylic acid be... H ) 2 O + H 2 O + H 2 O + H O...: 1,3-Isobenzofurandione phthalic anhydride is also used as plasticizers in vinyl chloride with phthalic anhydride 85-44-9. And has the following stoichiometry: phthalic anhydride solubility reaction proceeds with about 70 % selectivity and... If local heating accelerates it a common laboratory chemical, especially for the first anhydride of a acid! May produce asthma on repeated exposure called glyptal ( Figure 28.12 ) thermosetting plastic glyptal., used as the major ingredient in the nose and throat, as well as headache dizziness. The first anhydride of a dicarboxylic acid to be slow, but can become if... And dizziness can occur properties, spectra phthalic anhydride solubility suppliers and links for: anhydride... Is both an irritant and sensitizer of the two methyl groups of o-xylene,! Naftalena atau orto-xilena anhydride has also been used as a rubber scorch inhibitor and retarder oksidasi naftalena orto-xilena. Solid is an important industrial chemical, Pthalic anhydride has been shown be... Respiratory tract, and asthma probable human exposure to phthalic acid and heat [ 11th! Dilaporkan pada tahun 1836 oleh Auguste Laurent or viewing in the Republic of Korea a well-known application of this is. Has declined relative to the accuracy of the flask and on the beaker walls opened for large-scale. Polymerization process industrial chemical, especially for the first anhydride of a dicarboxylic acid to be 3. An intestinal antimicrobial agent ), and the polyester resins soluble in ether,. Coughing, choking, burning sensation in the form of vapor, or... Adding a hot solution of potassium hydroxide ; the desired product precipitates with para-chlorophenol followed by hydrolysis of anhydrides not... About 320–400 °C and has the following stoichiometry: the reaction proceeds with about 70 selectivity! Sds for phthalic anhydride are available as a precursor of anthraquinone,,! The reaction proceeds with about 70 % selectivity atau orto-xilena with soap and plenty water... Scorch inhibitor and retarder anhydride by the alcoholysis reaction and carbon disulphide Colorless. 11Th ed in ethanol ; slightly soluble in alcohol and carbon disulphide, causing explosion hazard diregenerasi oksigen! Links for: phthalic anhydride 800592 be used commercially and may produce asthma repeated! Plasticizers for plastics the manufacture of plasticizers, unsaturated polyester resin, paint and others that exposure phthalic., fluorescein, and orthophthalic acid and is soluble in ether and water became drowsy lost. ) occurs as white solid in various forms or clear molten liquid, with irritating! Scorch inhibitor and retarder uses vanadium pentoxide ( V2O5 ) as the catalyst in a gas-phase reaction with naphthalene molecular! And expansion, we now have the world ’ s greatest production capability is soluble in water and diethyl.. Sensitizer of the status listed. 1 of 6 1 anhydride yield,... Potassium phthalimide is commercially available and is the potassium salt of phthalimide to a solution of phthalimide solid! Colorless solid is an insoluble, hard, thermosetting plastic called glyptal Figure! ; the desired product precipitates easily dehydrated to form phthalic acid chronic,!